Insights into functional mitral regurgitation despite preserved LVEF
نویسندگان
چکیده
منابع مشابه
Active adaptation of the tethered mitral valve: insights into a compensatory mechanism for functional mitral regurgitation.
BACKGROUND In patients with left ventricular infarction or dilatation, leaflet tethering by displaced papillary muscles frequently induces mitral regurgitation, which doubles mortality. Little is known about the biological potential of the mitral valve (MV) to compensate for ventricular remodeling. We tested the hypothesis that MV leaflet surface area increases over time with mechanical stretch...
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Ischemic mitral regurgitation is a common complication of the healing phase of myocardial infarction. A number of mechanisms have been invoked in its pathogenesis, including alterations of papillary muscle position, annular dynamics, and intraventricular synchrony. The echocardiographic hallmark of ischemic mitral regurgitation is systolic tethering of the mitral valve leaflets away from the an...
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Chronic ischemic mitral regurgitation (cIMR) remains a vexing problem for a large number of patients and their respective clinicians. It is estimated that 2 million Americans experience cIMR, and this number is likely to increase with an aging general population and improved survival rates for myocardial infarction.1 Despite the large number of patients with this disease, relatively few patient...
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BACKGROUND Left atrial remodeling caused by persistent atrial fibrillation (AF) causes atrial functional mitral regurgitation (MR), even though left ventricular (LV) remodeling and organic changes of the mitral leaflets are lacking. The detailed mechanism of atrial functional MR has not been fully investigated. METHODSANDRESULTS Of 1,167 patients with AF who underwent 3D transesophageal echoc...
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BACKGROUND Three-dimensional dynamics of the 3 individual scallops within the posterior mitral leaflet during acute ischemic mitral regurgitations have not been previously measured. METHODS Radiopaque markers were sutured to the mitral annulus, papillary muscle tips, and leaflet edges in 13 sheep. Immediately postoperatively, under open-chest conditions, 3-D marker coordinates were obtained u...
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ژورنال
عنوان ژورنال: Archives of Cardiovascular Diseases
سال: 2011
ISSN: 1875-2136
DOI: 10.1016/j.acvd.2010.04.010